LGD 3303 (Liquid Form) – Product Details
- This liquid is offered as 30ml / 17mg per ml / 510mg
LGD 3303, just like LGD 4033, is a selective androgen receptor modulator (SARM). Research has shown that LGD 3303 could potentially cross the blood-brain barrier. This SARM has also been proven to possess the potential to increase bone mineral density (BMD) in the femur and spine areas in rats.
Animal research has further demonstrated that LGD 3303 may potentially enhance the sexual preference of females for males, provided females had previous sexual experience. Aside from that, LGD 3303 treatment increased female rats’ sexual behavior and motivation to mate.
- CAS Number is stated as 917891-35-1, 1196133-39-7
- Molar Mass is 342.75 g·mol−1
- It has a Chemical Formula of C16H14ClF3N2O
- IUPAC Name is 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one
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What is LGD 3303?
LGD 3303 is a novel selective androgen receptor modulator (SARM). It was initially developed by Ligand Pharmaceuticals as a potential treatment for osteoporosis. Research has shown that LGD 3303 is non-steroidal, non-aromatizable androgens, and may effectively cross the blood-brain barrier. [R]
LGD 3303 has demonstrated the potential ability to enhance sexual libido in female rats. In an animal study, this SARM increased the female rats’ sexual behavior, motivation to mate, and sexual preference for males. The last effect was observed in females who had prior sexual experience. [R]
In an animal model of postmenopausal osteoporosis, LGD-3303 was found to be potentially more effective than the current standard treatment for increasing bone mineral density (BMD) in the femur. In the lumbar spine, LGD-3303 was as effective as the standard treatment in increasing BMD. [R]
Results from the above study demonstrate that LGD 3303 might be a potentially useful agent for treating postmenopausal osteoporosis, either as a single agent or in combination with conventional bisphosphonate therapy. BehemothLabz sells LGD 3303 for laboratory research use only.
How Does LGD 3303 Work?
Multiple studies have shown that LGD-3303 may potentially stimulate anabolic actions in the skeleton and muscle tissue but with reduced trophic effects on the prostate gland. This indicates that LGD-3303 may be more tissue-selective than testosterone, DHT, and steroidal androgens. [R][R][R]
A pre-clinical study found that LGD-3303 potentially completely inhibited muscle weight loss artificially caused by androgen deprivation (ORDX). This was at an oral dose of 1 mg/kg/day. At higher doses, LGD-3303 had the potential to increase muscle weight above eugonadal levels. [R]
LGD-3303 Research
Although multiple clinical studies have been conducted on LGD-3303, this novel SARM has yet to attract clinical research. Nevertheless, the available data shows that LGD-3033 is capable of potentially increasing lean muscle mass, enhancing bone mineral density, and improving sexual libido.
LGD-3303 and Muscle Growth
In a 2007 pre-clinical study, LGD-3303 was found to potentially completely inhibit muscle weight loss caused by androgen deprivation. At higher doses, this SARM could significantly increase the animals’ muscle mass above eugonadal (healthy functioning gonads) levels. [R]
Results from this study make it clear that LGD-3303 has the potential to stimulate muscle anabolism. The study also established that LGD-3033 may maintain greater efficacy on muscle than the prostate. This is encouraging because it suggests that LGD-3303’s tissue specificity will be maintained in humans.
LGD-3303 and Osteoporosis
A three-month study examined the effects of LGD-3303 on bone density and strength in ovariectomized osteopenic rats. Results from the study show that repeated oral doses of LGD-3303 were more effective than the standard treatment for increasing BMD in the femur. [R]
In the lumbar spine, this SARM was found to be as effective as the conventional treatment in increasing BMD. These data suggest that LGD-3303 may provide a safe and effective new compound for the treatment of osteoporosis, including in patients who respond inadequately to the standard treatment.
LGD-3303 and Sexual Libido
In a study involving gonadectomized female rats, LGD-3303 was found to enhance the sexual preference of females for males after 1 or 7 days of treatment. This SARM was also able to increase the female rats’ sexual behavior and their motivation to mate. [R]
These data support the concept that LGD-3303 can potentially stimulate aspects of female sexual behavior. It also lends credence to the hypothesis that LGD-3303 may serve as a potential treatment for women test subjects with sexual desire disorders.
LGD-3303 and Fat Loss
LGD-3303 decreased the inguinal fat pad weight (mass of closely packed fat cells) in androgen-deficient female rats, both as a solo agent and in combination with another compound. In contrast, the compound wasn’t able to stimulate a decrease in fat pad weight when administered as a single agent. [R]
Frequently Asked Questions
Does LGD-3303 Increase Nitrogen Retention?
None of the studies on LGD-3303 mention anything about the potential effects of this SARM on nitrogen or water retention. More research is thus needed to verify or repudiate this claim.
What is the Half-life of LGD-3303?
LGD-3303 has a relatively short half-life of 6 hours.
Where to Buy LGD 3303 for Sale?
BehemothLabz is the best place to buy LGD 3303 online.
We have been around since 2014, supplying the highest-quality research compounds money can buy. All of our products come with a 100% satisfaction guarantee, free shipping, and a money-back guarantee. We carry multiple research chemicals.
Summary
LGD-3303 has demonstrated the potential ability to increase muscle mass, strengthen bones, and improve sexual libido in animal studies. However, in the absence of clinical research, randomized, placebo-controlled trials are needed to investigate its safety and efficacy.
BehemothLabz doesn’t sell LGD 3303 for human consumption.
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