Enclomiphene Citrate (Liquid) – Product Details

Enclomiphene, also recognized as Enclomiphene citrate, is a research chemical found to stimulate the release of follicle-stimulating hormone, which can increase testosterone levels in men without affecting the sperm’s normal range. This boost in testosterone has been shown to have benefits such as maintaining sperm counts and improving fertility.

• CAS Number: 7599-79-3
• Molecular weight: 598.08 g/mol
• Chemical Formula: C26H28ClNO.C6H8O7
• IUPAC Name: 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethyl-ethanamine 2-hydroxypropane-1,2,3-tricarboxylate
• Synonyms: Enclomiphene citrate is also known by its brand name Androxal, as well as the following synonyms: Zuclomiphene citrate, Enclomid, Androxene, Enclomifene citrate, and Androxal citrate.

What is Enclomiphene Citrate?

Enclomiphene citrate is a selective estrogen receptor modulator (SERM) that is used to treat secondary hypogonadism in men. It works by decreasing serum luteinizing hormone (LH), which in turn reduces the amount of estrogen produced by the body. By doing so, enclomiphene citrate stimulates the release of follicle-stimulating hormone (FSH), which can increase serum total testosterone levels.

This effect on LH and FSH is mediated by the enclomiphene citrate chemical structure, which binds to estrogen receptors in certain areas of the brain to regulate hormone levels.

Possible Uses of Enclomiphene Citrate

Enclomiphene citrate is a research chemical and should only be used under the guidance of qualified professionals. Here are some possible benefits of using enclomiphene citrate:

Possibly Decreases Serum Luteinizing Hormone (LH)

Enclomiphene citrate treatment has decreased serum LH levels in men with secondary hypogonadism, leading to increased testosterone production. A study involving primary sheep pituitary cells showed that enclomiphene citrate could decrease LH secretion in a dose-dependent manner. [R]

May Increase Serum Testosterone Levels

Enclomiphene citrate has been shown to have the potential to increase serum total testosterone levels in men with secondary hypogonadism. A clinical trial involving intact or castrated rats showed that enclomiphene citrate increased serum testosterone levels in a dose-dependent manner. [R]

Potentially Preserves Sperm Counts

Enclomiphene citrate treatment has been found to potentially maintain or increase sperm counts in men with secondary hypogonadism. A study involving topical testosterone replacement therapy showed that enclomiphene citrate could preserve sperm counts in obese hypogonadal men. [R]

May Increase Libido

Enclomiphene citrate treatment has been found to potentially increase libido in men with secondary hypogonadism. A clinical study involving men with ovarian dysfunction showed that enclomiphene citrate was able to potentially increase libido in a significant number of participants. [R]

It is important to note that enclomiphene citrate should only be used under the guidance of qualified professionals, as well as considering the risks and potential side effects.

The references cited above provide further information on the studies and research involving enclomiphene citrate.

How Does Enclomiphene Citrate Work

Enclomiphene citrate is a selective estrogen receptor modulator (SERM) structurally similar to clomiphene citrate. Its mechanism of action involves binding to estrogen receptors in the hypothalamus and pituitary gland, thereby blocking negative feedback inhibition and increasing follicle-stimulating hormone (FSH) secretion.

This increase in FSH stimulates the production of testosterone and spermatogenesis. Additionally, enclomiphene citrate inhibits the aromatase enzyme, which converts testosterone to estrogen, increasing testosterone levels. This increase in testosterone can lead to an increase in libido and sex drive.

Enclomiphene citrate may potentially address infertility in men by increasing testosterone levels and inhibiting spermatogenesis.

However, the exact mechanisms of how enclomiphene citrate affects libido and sex drive are still under investigation.

Safety and Side Effects

Enclomiphene citrate may have potential applications, but it can cause side effects. Some common side effects of enclomiphene citrate include headaches, hot flashes, mood changes, and nausea.

More serious side effects are rare but can include blood clots, vision changes, and allergic reactions. It’s important to discuss the potential risks and benefits of enclomiphene citrate with a healthcare professional before use.

Frequently Asked Questions

Is Enclomiphene Citrate safe?

Certain studies regarding enclomiphene citrate suggest that this research chemical could promote specific health advantages. Nevertheless, it is not recommended for human use because more large-scale studies are needed to confirm its benefits.

Does Enclomiphene have the potential to increase testicle size?

Early research studies show that Enclomiphene citrate may have the potential to increase testicular size in some men with low testosterone levels. Testicular volume is an essential indicator of testicular health and function. Studies have shown that treatment with enclomiphene citrate can increase testicular volume and improve spermatogenesis in men with hypogonadism.

However, the effects of enclomiphene citrate on testicular size may vary depending on individual factors such as age, baseline testosterone levels, and the duration and dose of treatment.

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Summary

Enclomiphene citrate has been widely studied for its potential benefits in research and human use. Some studies have suggested that enclomiphene citrate can increase testosterone production in men with low testosterone levels, improve fertility in women with polycystic ovary syndrome, and increase bone mineral density in postmenopausal women.

In addition, enclomiphene citrate has been shown to increase the concentration of luteinizing hormone and follicle-stimulating hormone, which can improve reproductive function.

However, it’s important to note that enclomiphene citrate has not yet been approved by the FDA for any medical use. Further research is needed to fully understand its potential benefits and risks.

This is for informational purposes only and should not be construed as medical advice. Consult a healthcare professional before using any medication or supplement for research usage.